The protein kinase Mec1 (ATR ortholog) and its partner Ddc2 (ATRIP ortholog) play a key role in DNA damage checkpoint responses in budding yeast. Previous studies have established the model in which Ddc1. a subunit of the checkpoint clamp. and Dpb11. https://www.parisnaturalfoodes.shop/product-category/shea-butter-olive-oil/