Abstract Peripheral nerve injury can lead to remodeling of brain circuits. and this can cause chronification of pain. We have recently reported that male mice subjected to spared injury of the sciatic nerve undergo changes in the function of the medial prefrontal cortex (mPFC) that culminate in reduced output of layer 5 pyramidal cells. More recently. https://fitnessgravesyardes.shop/product-category/console-front/