For homeostasis. lingual taste papilla organs require regulation of epithelial cell survival and renewal. with sustained innervation and stromal interactions. To investigate a role for Hedgehog/GLI signaling in adult taste organs we used a panel of conditional mouse models to manipulate GLI activity within epithelial cells of the fungiform and circumvallate papillae. https://www.roneverhart.com/Almanac-Sunshine-Opportunity-Barrel-Aged-Hibiscus-Sour-single/